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Citrus Aurantium Extract CAS10236-47-2 Naringin
Product name | Naringin |
CAS No. | 10236-47-2 |
Molecular formula | C27H32O14 |
Molecular weight | 580.53 |
Purity | 99% |
Appearance | White or almost white powder |
Naringin is extracted from grapefruit fruit. It's a compound capable of exerting many health benefits and helpful in preventing and treating many conditions and illnesses. This bioflavonoid has antioxidant and antifungal properties, and as such may help prevent cancer and atherosclerosis (hardening of arteries), as well as a few other ailments. Naringin also works synergistically with other nutrients, increasing the bio-availability and therefore maximizing the health benefits of these nutrients. It could be used as bitter agent in beer and coffee, and formulas containing large percentage of sugar.
Function
1. Antioxidant effect
Naringin was shown to possess strong superoxide scavenging activity and xanthine oxidase inhibitory activity, and the ability to quench ROS, decrease the oxygen-free radical-stimulated K+ permeability, and inhibit lipid peroxidation.
2. Anti-inflammatory effect
Naringin has been shown to mediate its anti-inflammatory effect by inhibiting IL-8, MCP-1, and MIP-1α secretion and mRNA expression, and by inhibiting the phosphorylation of ERK1/2, JNK, and p38 MAPK, probably through blocking the activation of the NF-κB and MAPK signaling pathways.
3. Cardioprotective effects: potentially retard the progression of atherosclerosis
4. Neuroprotection: beneficial effect in alleviation of Alzheimers disease
5. Bone diseases: augmented osteoblastic activity; improve osteogenic proliferation and differentiation in MC3T3-E1 cells; prevent bone loss.
6. Gastrointestinal tract: reduced the ulcer index and improved gastric mucosal morphology
Application
1. Applied in pharmaceutical field, in the form of tablet or capsule, for provention or alleviation of atherosclerosis, Alzheimers, gastrointestinal disorder, or bone loss.
2. Applied in food and drink industries, as bitter agent or taste modifier.
3. Applied in cosmetic products, for skin nourishing or redness alleviation.
4. As raw material for preparation of dihydrochalcone sweeteners like neohesperidin DC(NHDC) and naringin DC(NADC).
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